Opinion Piece: Viruses and Type 1 Diabetes

We are pleased to announce a new opinion publication by Dr. Knut Dahl-Jørgensen from Oslo University Hospital, featured in the latest issue of Trends in Molecular Medicine. Titled “Virus as the Cause of Type 1 Diabetes,” the article explores the theory that a persistent, low-grade enterovirus infection may trigger the autoimmune response leading to Type 1 Diabetes (T1D) in genetically predisposed individuals.

The publication draws on data from the Diabetes Virus Detection (DiViD) study, which identified enterovirus presence in the pancreas of newly diagnosed T1D patients. Key findings include:

  • The detection of live, replicating enteroviruses in the pancreatic tissue at diagnosis.
  • Evidence suggests that antiviral treatments can preserve residual insulin production in newly diagnosed patients.

This research supports the notion that early antiviral intervention could alter the disease progression, potentially offering new T1D prevention and management strategies. Dr. Knut Dahl-Jørgensen’s work significantly shifts our understanding of T1D pathogenesis and opens new possibilities for therapeutic approaches.

For a detailed read, access the full publication.

Stay tuned for more updates on this promising research!